ROKIT Healthcare announced the launch of the Dr. INVIVO 4D6, a bioreactor-based bioprinting platform with a built-in cell incubator and low-temperature plasma sterilizer as the first of its kind. It is designed and built with the vision of in-hospital manufacturing and offers a controlled cellular environment in aseptic conditions in combination with the complex biofabrication technologies of six rotary printheads. ROKIT Healthcare is a South Korea-based regenerative medicine solutions company that develops hardware, software, and clinical application platforms employing 4D bioprinting technology for customized human organ and tissue regeneration.
Chief Executive Officer at ROKIT Healthcare, Seok Hwan You, explains: “Bioprinting right by the bedside inside the operating theatre means minimized time, risks, and costs in the transfer of patient cells to the bioprinter and in the transfer of printed tissues back to the patient. It is a new kind of point-of-care, personalized healthcare solution that maximizes the benefits of autologous regenerative medicine technologies. Dr. INVIVO 4D6, which we call the Organ Regenerator, is designed to pave the way with features that have been added after feedback from physicians and scientists.”
Features on the Dr. INVIVO 4D6 from ROKIT Healthcare
Achieving three-dimensional architecture is just one of several factors to consider in tissue engineering. Cell environment factors, like incubation temperature, oxygen/carbon dioxide level, and humidity are key to successful human tissue and organ development with optimal cell viability and functionality. Moving beyond the capacity to dispense cells and biomaterials with multiple printheads, Dr. INVIVO 4D6 offers an integrated system to meet clinical needs in human tissue engineering and its translational applications.
Dr. INVIVO 4D6 optimizes tissue engineering and regenerative medicine research with:
- Built-in cell incubator with temperature, humidity and CO2 control
- 6 printheads for complex tissue fabrication with hydrogels, filaments, polymer pellets, and diverse FDA-approved materials
- Complete particle control with circular air flow generation technology, much like a biosafety cabinet
- High-throughput to the max with up to 384-well tissue screening and assay development
Translation of Bioprinting in the Operating Room
In addition to being a bioprinter manufacturer, ROKIT Healthcare works as a medical contractor that partners with state agencies, biotech firms and academic research centers to develop applications for bioprinting technology in the hospital operating room. ROKIT Healthcare has been awarded a $3 million grant by the South Korean government to co-develop an in-situ 3D bioprinting system for skin regeneration. Since 2019, ROKIT Healthcare has partnered with specialty plastic surgery hospitals around the world to offer 3D scan-print skin regeneration platforms for patients suffering from chronic diabetic foot ulcers and burns. The company has completed clinical studies in India and Korea.
Founded in 2012 and active in more than 50 countries, the company is advancing the scientific and healthcare revolution in regenerative medicine by providing on-demand human tissue manufacturing solutions in vivo and in vitro.
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